ADMA is a naturally occurring compound that blocks nitric oxide production in the lining of blood vessels. Nitric oxide keeps vessels relaxed and flexible, so higher ADMA means stiffer, less responsive vessels.
Elevated ADMA is an early marker of endothelial dysfunction — vessel lining that has lost some of its ability to dilate — and is associated with higher cardiovascular risk independent of cholesterol. It is often raised alongside insulin resistance, high homocysteine and reduced kidney function.
Optimal ADMA (Asymmetric Dimethylarginine): 0-0.55 µmol/L.
Typically re-tested every 26 weeks.