The calcium-to-albumin ratio corrects serum calcium for the albumin carrier protein, because serum calcium alone can be misleading when albumin is low (falsely low calcium) or high.
Used in clinical medicine to flag parathyroid dysfunction: elevated ratio suggests primary hyperparathyroidism or calcium dysregulation. In functional medicine, it's a supporting marker for calcium status alongside ionized calcium and vitamin D.
Optimal Calcium:Albumin Ratio: 2.1-2.5 ratio.
Typically re-tested every 16 weeks.