HDL Medium measures the count of medium-sized HDL particles in the ION lipoprotein panel, a subfraction between small (nascent) and large (mature) HDL.
The HDL subfraction literature is less mature than LDL subfractions. Medium HDL reflects particles in the process of maturing from small/discoidal to large/spherical forms. Clinical interpretation is supportive rather than decisive. Focus on HDL-C, ApoA-1, and HDL Large for cardioprotection.
Optimal HDL Medium (ION): 10000-20000 nmol/L.
Typically re-tested every 12 weeks.