LDL Large measures the count of large, buoyant LDL particles. These particles are the least atherogenic subfraction. They penetrate artery walls less easily and are more efficiently cleared from circulation than their smaller counterparts.
A profile shifted toward large LDL reflects better metabolic health and lower cardiovascular risk per unit of LDL-C. This pattern is characteristic of people with good insulin sensitivity, adequate omega-3 intake, and regular physical activity.
Optimal LDL Large (ION): 200-600 nmol/L.
Typically re-tested every 12 weeks.