Lipoprotein(a), pronounced "L-P-little-a," is an LDL-like particle with an extra protein called apolipoprotein(a) attached. Its level is ~90% genetically determined and typically stable across a lifetime, meaning one test can settle the question for most adults.
Elevated Lp(a) is an independent cardiovascular risk factor that operates beyond standard cholesterol markers. It promotes atherosclerosis, thrombosis, and aortic valve calcification. Roughly 20% of the population has meaningfully elevated levels, and the marker is underordered in standard clinical practice. Testing once in adulthood is enough for most people, and a normal result removes this as an ongoing concern.
Optimal Lipoprotein (a), molar: 0-18 nmol/L.
Typically re-tested every 52 weeks.