A/G ratio = albumin ÷ globulin, where globulin = total protein − albumin.
What your result means
A commonly cited normal A/G ratio is 1.2 to 2.0, and some laboratory tables print a wider 1.0 to 2.5.
A low ratio means relatively more globulin or less albumin. It can reflect inflammation, liver or kidney changes, or immune activity, and it is read alongside the individual albumin and globulin values.
A high ratio means relatively less globulin, which is less common and is also read with the individual values.
Your own lab's printed range and your clinician's read of your history come first; this calculator is educational and is not a diagnosis.
Globulin is calculated first as total protein minus albumin, then albumin is divided by globulin. Both values come from a standard metabolic panel.
What does a low A/G ratio mean?
It means globulin is high relative to albumin, or albumin is low. It is a clue rather than a diagnosis, and a clinician reads it with the rest of the panel.
Do I need a separate test for the A/G ratio?
No. Most comprehensive metabolic panels report albumin and total protein, which is all the calculation needs.