HOMA-IR Calculator: Insulin Resistance Score

How it is calculated

HOMA-IR = fasting insulin (µU/mL) × fasting glucose (mg/dL) ÷ 405 (or glucose in mmol/L ÷ 22.5).

What your result means

• In a large study of healthy adults, the reference range was about 0.39 to 2.86, with almost no difference between men and women.
• Insulin assays differ between laboratories, so HOMA-IR values from different labs are not always comparable.
• Your own lab's printed range and your clinician's read of your history come first; this calculator is educational and is not a diagnosis.

Test the inputs

The Metabolic and insulin panel measures the values this calculator uses. Related: fasting insulin, fasting glucose, hemoglobin a1c.

Common questions

Do both values need to be fasting?

Yes. HOMA-IR is defined on fasting insulin and fasting glucose from the same draw.

What is a normal HOMA-IR?

Healthy adults in a large study ranged from about 0.39 to 2.86. Labs and clinicians may use different cut-offs.

Can I use glucose in mmol/L?

Yes. With glucose in mmol/L, divide insulin times glucose by 22.5 instead of 405.

References

1. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 1985.