Bioidentical estrogen as a patch, pill or vaginal cream
From $259/mo with a 6-month plan A licensed provider reviews your intake and decides whether it's appropriate for you. Your provider picks your starting dose and adjusts it as you go.
100% online visit
Licensed providers in all 50 states
Ships in plain packaging
Message your care team anytime
How getting estradiol works
Tell us about your health. A short online intake: your history, medications and goals.
A licensed provider reviews it. They decide whether it's right for you and set your dose.
Treatment ships to you. In plain packaging. Track it, and message your care team, from Care.
What it is
Estradiol is the main estrogen your ovaries make before menopause. Replacing it is the most effective treatment for hot flashes and night sweats.
How it works in the body
It restores estrogen levels that fall in perimenopause and menopause. The patch delivers it steadily through the skin; vaginal cream treats local symptoms.
What to expect
Weeks 2–4: Hot flashes and night sweats often ease first.
Months 2–3: Sleep, mood and vaginal comfort improve for many.
May be a good fit if
Hot flashes, night sweats or poor sleep around menopause
Vaginal dryness or discomfort
Probably not for you if
History of breast or uterine cancer
History of blood clots or stroke
Unexplained vaginal bleeding
Doses your provider can prescribe
Estradiol 0.025MG
Estradiol 0.0375 MG
Estradiol 0.05 MG
Estradiol 0.075MG
Estradiol 0.1 MG
C-Estradiol
Estradiol
Common side effects
Breast tenderness
Spotting
Headache
Safety
A licensed provider reviews your intake and decides whether it's appropriate for you.
This isn't a full list. Your provider reviews your history and medications before prescribing.